1-(tert-butyl) 3-ethyl trans-4-(3-(trifluoromethyl)phenyl)pyrrolidine-1,3-dicarboxylate - Names and Identifiers
1-(tert-butyl) 3-ethyl trans-4-(3-(trifluoromethyl)phenyl)pyrrolidine-1,3-dicarboxylate - Introduction
1-(tert-butyl) 3-ethyltrans-4-(3-(trifluoromethyl) phenyl) pyrrolidine-L, 3-dicarboxylate is a compound having the formula C19H23F3NO4.
Nature:
-Appearance: Colorless crystalline solid.
-Melting point: About 50-53 degrees Celsius.
-Solubility: Soluble in some organic solvents, such as chloroform, dichloromethane and ethanol.
Use:
-Chemical reagents: used in organic synthesis reactions, such as metal-catalyzed C- C bond formation reactions, Cyclization Reactions, etc.
-Drug intermediates: can be used to synthesize drugs and other biologically active compounds.
Method:
One method of synthesis is by esterification of pyrrolidine -1,3-dicarboxylic acid. Specific steps involve the catalyzed esterification of tert-butyl copper iodide and the condensation of the corresponding alcohol and nitrile.
Safety Information:
-For the safety of this compound, general laboratory safety procedures should be followed.
-Direct contact with skin and eyes must be avoided.
-During use, good ventilation should be adopted to avoid inhaling aerosols or dust.
-should be stored in a dry, cool place, away from fire and oxidant.
In General, 1-(tert-butyl) 3-ethyltrans-4-(3-(trifluoromethyl) phenyl) pyrrolidine -1, 3-Dicarboxylate is a commonly used reagent in organic synthesis, which has a wide range of application potential, and should follow relevant safety operating procedures.
Last Update：2024-04-09 15:18:04